Despite the text that tries to explain this, I don't think the current documentation for the Run Now feature is clear to new users. What isn't clear is that the Trigger and initial Filter condition are treated together and both will be ignored when using Run Now. Besides the help text description, the visuals for this block support show contrasting colors for Trigger and Filter accompanied by large text highlighting the Trigger area of the block.
A few ways to improve here so I'll list a couple:
Referencing post: